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ResearcherID: AAC-9166-2020

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Employment (3)

University College London: London, GB

2020-05-01 to present | Honorary Associate Professor (Institute of Child Health )
Employment
Source: Self-asserted source
Ashirwad Merve

National Hospital for Neurology and Neurosurgery: London, GB

2018-09-01 to present | Consultant Neuropathologist (Neuropathology)
Employment
Source: Self-asserted source
Ashirwad Merve

Great Ormond Street Hospital for Children NHS Foundation Trust: London, GB

2018-09-01 to present | Consultant Paediatric Neuropathologist (Histopathology )
Employment
Source: Self-asserted source
Ashirwad Merve

Education and qualifications (6)

Royal College of Pathologists: London, GB

2014 to 2018 | FRCPath (Neuropathology)
Education
Source: Self-asserted source
Ashirwad Merve

Royal College of Physicians: London, GB

2014 to 2014 | DLM (Legal Medicine)
Education
Source: Self-asserted source
Ashirwad Merve

Queen Mary University of London: London, GB

2009 to 2014 | PhD (Neurosciences)
Qualification
Source: Self-asserted source
Ashirwad Merve

Manipal Hospital: Bengaluru, Karnataka, IN

2013 to 2013 | E-MBA (Hospital Management)
Qualification
Source: Self-asserted source
Ashirwad Merve

Royal College of Surgeons of England: London, GB

2003 to 2005 | DO-HNS (ENT / Head & Neck Surgery)
Qualification
Source: Self-asserted source
Ashirwad Merve

Rajiv Gandhi University of Health Sciences: Bengaluru, IN

1997 to 2002 | MBBS (Medicine)
Qualification
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Ashirwad Merve

Professional activities (2)

British Neuropsychological Society: London, GB

2023-03 to present | Chair (Professional Affairs Committee)
Membership
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Ashirwad Merve

Royal College of Pathologists: London, GB

2021-03 to present | Member (Specialist Advisory Committee )
Membership
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Ashirwad Merve

Funding (3)

NIHR Clinical Lecturer

2014-08 to 2018-08 | Salary award
National Institute of Health Research (NIHR) (London, GB)
Source: Self-asserted source
Ashirwad Merve

The Bmi1/BMP connection in medulloblastoma pathogenesis

2010-11-01 to 2013-10-31 | Grant
Medical Research Council (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.2753458
GRANT_NUMBER: G0902001
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Ashirwad Merve via DimensionsWizard

NIHR Academic Clinical Fellow

2008 to 2014 | Contract
NIHR and London Deanery (London, GB)
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Ashirwad Merve

Works (50 of 97)

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Page 1 of 2

Case Report: Novel neuroinflammatory syndrome associated with TONSL-related SPONASTRIME Dysplasia [version 1; peer review: awaiting peer review]

2025-06-09 | Journal article
DOI: 10.12688/wellcomeopenres.23663.1
Part of ISSN: 2398-502X
Funded by GRANT_NUMBER: 207556
Funded by GRANT_NUMBER: V5019
Contributors: Rob Forsyth; Eleri Williams; Sophie L. Cooke; Michael Wright; Karin R. Engelhardt; Dipayan Mitra; Ashirwad Merve; Abhijit Joshi; Grant S. Stewart; Sophie Hambleton et al.
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Wellcome Open Research
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Biallelic NSUN3 Variants Cause Diverse Phenotypic Spectrum Disease: From Isolated Optic Atrophy to Severe Early-Onset Mitochondrial Disorder.

Investigative ophthalmology & visual science
2025-06-01 | Journal article
DOI: 10.1167/iovs.66.6.17
PMID: 40465263
Contributors: Jurkute N; Brennenstuhl H; Kustermann M; Van Haute L; Mutti CD; Bugiardini E; Handa T; Shimura M; Petzold A; Acheson J et al.
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Ashirwad Merve

Testing Meningiomas With Methylation Arrays: Insights and Recommendations From a Large Single‐Centre Study

Neuropathology and Applied Neurobiology
2025-05-13 | Journal article
DOI: 10.1111/nan.70018
Part of ISSN: 1365-2990
Contributors: Fernanda Ruiz; Rossella Rispoli; Zane Jaunmuktane; Ashirwad Merve; Linda D'Antona; Monika Dutt; Felix Sahm; Sebastian Brandner
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Safety and Diagnostic Utility of Brain Biopsy and Metagenomics in Decision-Making for Patients with Inborn Errors of Immunity (IEI) and Unexplained Neurological Manifestations

Journal of Clinical Immunology
2025-04-16 | Journal article
DOI: 10.1007/s10875-025-01878-y
Part of ISSN: 1573-2592
Contributors: Jesmeen Maimaris; Julia Payne; Adriel Roa-Bautista; Judith Breuer; Nathaniel Storey; Sofia Morfopoulou; Alasdair Bamford; Felice D’Arco; Kimberly Gilmour; Kristian Aquilina et al.
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E020 A life-threatening case of myositis following infliximab and azathioprine co-administration

Rheumatology
2025-04-01 | Journal article
DOI: 10.1093/rheumatology/keaf142.257
Part of ISSN: 1462-0332
Contributors: Jan Nouza; Matthew Colquhoun; Sabreen Ali; Ashirwad Merve; Stuart Viegas; Anne Kinderlerer
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Impact of non-invasive post-mortem micro-CT imaging on a fetal autopsy service: a single centre retrospective study

Clinical Radiology
2024-10 | Journal article
DOI: 10.1016/j.crad.2024.06.015
Part of ISSN: 0009-9260
Contributors: I.C. Simcock; O.J. Arthurs; J.C. Hutchinson; N.J. Sebire; T.S. Jacques; T. Sekar; S.C. Shelmerdine; D. Alvarez; V. Lee; E. Yates et al.
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Paediatric low-grade glioma: the role of classical pathology in integrated diagnostic practice

Child's Nervous System
2024-10 | Journal article
DOI: 10.1007/s00381-024-06591-6
Contributors: Thomas J. Stone; Ashirwad Merve; Fernanda Valerio; Shireena A. Yasin; Thomas S. Jacques
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Author Correction: A CCG expansion in ABCD3 causes oculopharyngodistal myopathy in individuals of European ancestry

Nature Communications
2024-10-17 | Journal article
DOI: 10.1038/s41467-024-53151-2
Part of ISSN: 2041-1723
Contributors: Andrea Cortese; Sarah J. Beecroft; Stefano Facchini; Riccardo Curro; Macarena Cabrera-Serrano; Igor Stevanovski; Sanjog R. Chintalaphani; Hasindu Gamaarachchi; Ben Weisburd; Chiara Folland et al.
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Decision making for health‐related research outcomes that alter diagnosis: A model from paediatric brain tumours

Neuropathology and Applied Neurobiology
2024-08 | Journal article
DOI: 10.1111/nan.12994
Part of ISSN: 0305-1846
Part of ISSN: 1365-2990
Contributors: Jessica C. Pickles; Kristian Aquilina; Jane Chalker; Christine Dahl; Abel Devadass; Kshitij Mankad; Ashirwad Merve; Munaza Ahmed; James A. R. Nicoll; Tabitha Bloom et al.
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A CCG expansion in ABCD3 causes oculopharyngodistal myopathy in individuals of European ancestry

Nature Communications
2024-07-27 | Journal article
DOI: 10.1038/s41467-024-49950-2
Part of ISSN: 2041-1723
Contributors: Andrea Cortese; Sarah J. Beecroft; Stefano Facchini; Riccardo Curro; Macarena Cabrera-Serrano; Igor Stevanovski; Sanjog R. Chintalaphani; Hasindu Gamaarachchi; Ben Weisburd; Chiara Folland et al.
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<i>PYROXD1</i>-associated myopathy

BMJ Case Reports
2024-03 | Journal article
DOI: 10.1136/bcr-2024-259907
Part of ISSN: 1757-790X
Contributors: Matthew Selwyn D'Costa; Enrico Bugiardini; Ashirwad Merve; Jasper M Morrow
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Primary orbital rhabdoid tumour masquerading as atypical persistent foetal vasculature

BMJ Case Reports
2024-01 | Journal article
DOI: 10.1136/bcr-2022-250776
Part of ISSN: 1757-790X
Contributors: Catherine Douch; Ashirwad Merve; Kshitij Mankad; Mette Jorgensen
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Pediatric nasal chondromesenchymal hamartomas: a case series

Neuroradiology
2024-01-11 | Journal article
DOI: 10.1007/s00234-023-03276-w
Part of ISSN: 1432-1920
Contributors: Jernej Avsenik; Ibrahem Albalkhi; Sanjay P. Prabhu; Rupa Radhakrishnan; Robert Goetti; Alok Jaju; Ashirwad Merve; Asthik Biswas; Kshitij Mankad
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Germline homozygous missense DEPDC5 variants cause severe refractory early-onset epilepsy, macrocephaly and bilateral polymicrogyria

Human Molecular Genetics
2023 | Journal article
DOI: 10.1093/HMG/DDAC225
WOSUID: WOS:000868765200001
Contributors: Ververi, Athina; Zagaglia, Sara; Menzies, Lara; Baptista, Julia; Caswell, Richard; Baulac, Stephanie; Ellard, Sian; Lynch, Sally; Jacques, Thomas S.; Chawla, Maninder Singh et al.
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Translating metagenomics into clinical practice of complex paediatric neurological presentations

MedRxiv
2023 | Journal article
DOI: 10.1101/2023.06.02.23290816
WOSUID: PPRN:72850650
Contributors: Penner, Justin; Hassell, Jane; Brown, Julianne R; Mankad, Kshitij; Storey, Nathaniel; Atkinson, Laura; Ranganathan, Nisha; Lennon, Alexander; Lee, Jack C D; Champsas, Dimitrios et al.
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Review for "Toll‐like receptors and IL‐7 as potential biomarkers for immune‐mediated necrotizing myopathies"

2023-06-27 | Review
DOI: 10.1002/eji.202250326/v2/review2
Contributors: Ashirwad Merve
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Review for "Toll‐like receptors and IL‐7 as potential biomarkers for immune‐mediated necrotizing myopathies"

2023-02-15 | Review
DOI: 10.1002/eji.202250326/v1/review1
Contributors: Ashirwad Merve
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A Comparative Study of CSF Cytology During and Before COVID-19 Pandemic

The Journal of Pathology
2022 | Journal article
WOSUID: WOS:000783595400067
Contributors: Sabarigirivasan, V.; Merve, A.
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Andersen-Tawil syndrome: deep phenotyping reveals significant cardiac and neuromuscular morbidity

Brain
2022 | Journal article
DOI: 10.1093/BRAIN/AWAB445
WOSUID: WOS:000780231500001
Contributors: Vivekanandam, Vinojini; Mannikko, Roope; Skorupinska, Iwona; Germain, Louise; Gray, Belinda; Wedderburn, Sarah; Kozyra, Damian; Sud, Richa; James, Natalie; Holmes, Sarah et al.
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Bi-allelic loss-of-function OBSCN variants predispose individuals to severe recurrent rhabdomyolysis

Brain
2022 | Journal article
DOI: 10.1093/BRAIN/AWAB484
WOSUID: WOS:000839569500001
Contributors: Cabrera-Serrano, Macarena; Caccavelli, Laure; Savarese, Marco; Vihola, Anna; Jokela, Manu; Johari, Mridul; Capiod, Thierry; Madrange, Marine; Bugiardini, Enrico; Brady, Stefen et al.
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Congenital orbital teratoma: A case report with foetal presentation

Child's Nervous System
2022 | Journal article
DOI: 10.1007/S00381-022-05576-7
WOSUID: WOS:000823249800002
Contributors: Wheeler, Matthew; Pergoretti, Kelly; Gore, Sri; D'Arco, Felice; Merve, Ashirwad; Mankad, Kshitij
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DURABLE RESPONSE TO MTOR INHIBITOR AFTER FAILING CHECKPOINT INHIBITORS IN ULTRA-HYPERMUTATED HIGH GRADE GLIOMA IN CONTEXT OF CMMRD

Neuro-Oncology
2022 | Journal article
WOSUID: WOS:000840122400250
Contributors: Hegde, Kriti; Dahl, Christine; Depani, Sarita; Hargrave, Darren; Oostveen, Minou; Aguirregomezcorta, Fernando; Jeelani, Owase; Aquilina, Kristian; Gains, Jenny; Ching, Yen et al.
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Muscle biopsy in myositis: What the rheumatologist needs to know

Best Practice and Research in Clinical Rheumatology
2022 | Journal article
DOI: 10.1016/J.BERH.2022.101763
WOSUID: WOS:000878068100002
Contributors: Merve, Ashirwad; Schneider, Udo; Kara, Eleanna; Papadopoulou, Charalampia; Stenzel, Werner
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Repurposing Vandetanib plus Everolimus for the Treatment of <i>ACVR1</i>-Mutant Diffuse Intrinsic Pontine Glioma

Cancer Discovery
2022 | Journal article
DOI: 10.1158/2159-8290.CD-20-1201
WOSUID: WOS:000754375900001
Contributors: Carvalho, Diana M.; Richardson, Peter J.; Olaciregui, Nagore; Stankunaite, Reda; Lavarino, Cinzia; Molinari, Valeria; Corley, Elizabeth A.; Smith, Daniel P.; Ruddle, Ruth; Donovan, Adam et al.
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Atypical teratoid/rhabdoid tumours of the sellar region

Neuropathology and Applied Neurobiology
2021 | Journal article
WOSUID: WOS:000623940600020
Contributors: Deacon, Simon; Dow, Graham; Griffin, Matthew; Devadass, Abel; Merve, Ashirwad; Jacques, Thomas; Scott, Ian; Akhtar, Noreen; Paine, Simon
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Biallelic loss-of-function <i>OBSCN</i> variants predispose individuals to severe, recurrent rhabdomyolysis

Neuromuscular Disorders
2021 | Journal article
DOI: 10.1101/2021.06.04.447044
WOSUID: WOS:000697873700381
Contributors: Cabrera-Serrano, Macarena; Caccavelli, Laure; Savarese, Marco; Vihola, Anna; Jokela, Manu; Johari, Mridul; Capiod, Thierry; Madrange, Marine; Bugiardini, Enrico; Brady, Stefen et al.
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Constitutional mismatch repair deficiency (CMMRD) presenting with high-grade glioma, multiple developmental venous anomalies and malformations of cortical development-a multidisciplinary/multicentre approach and neuroimaging clues to clinching the diagnosis

Child's Nervous System
2021 | Journal article
DOI: 10.1007/S00381-020-04986-9
WOSUID: WOS:000594960500001
Contributors: Chhabda, Sahil; Sudhakar, Sniya; Mankad, Kshitij; Jorgensen, Mette; Carceller, Fernando; Jacques, Thomas S.; Merve, Ashirwad; Aizpurua, Miren; Chalker, Jane; Garimberti, Elisa et al.
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Ectopic thoracic meningioma: a diagnostically challenging case

BMJ Case Reports
2021 | Journal article
DOI: 10.1136/BCR-2021-242020
WOSUID: WOS:000656975900008
Contributors: Salehi, Mahan; Merve, Ashirwad; Yancheva, Slaveya; Kadlec, Jakub
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IDH Mutation in Medulloblastoma: A Diagnostic Challenge

Neuropathology and Applied Neurobiology
2021 | Journal article
WOSUID: WOS:000623940600017
Contributors: Nagaraju, Santhosh; Joshi, Abhijit; Merve, Ashirwad; Pohl, Ute
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Problem solving in clinical practice: an unusual cause of multifocal brain lesions

Archives of Disease in Childhood - Education and Practice
2021 | Journal article
DOI: 10.1136/ARCHDISCHILD-2020-319655
WOSUID: WOS:000700176100012
Contributors: Hodgson, Joshua Mark; Douch, Catherine; Hartley, Louise; Merve, Ashirwad; Devadass, Abel; Chatterjee, Fiona
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MRI Patterns in Pediatric CNS Hemophagocytic Lymphohistiocytosis

American Journal of Neuroradiology
2021-11-07 | Journal article
DOI: 10.3174/ajnr.A7292
Contributors: P. Malik; L. Antonini; P. Mannam; F.N. Aboobacker; A. Merve; K. Gilmour; K. Rao; S. Kumar; S.E. Mani; D. Eleftheriou et al.
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Progressive myoclonic epilepsy due to rare mitochondrial ND6 mutation, m.14487T&gt;C

BMJ Neurology Open
2021-06 | Journal article
DOI: 10.1136/bmjno-2021-000180
Part of ISSN: 2632-6140
Contributors: Anthony Khoo; Saadnah Naidu; Surapi Bhairavi Wijayendran; Ashirwad Merve; Fion Bremner; Meneka Kaur Sidhu
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c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism.

The Francis Crick Institute
2020 | Journal article
DOI: 10.25418/CRICK.11549676
Contributors: ; ; Nicola Pomella; Serena Acquati; ; Anaelle Dumas; Gabriel Rosser; ; Jennie Jeyapalan; Silvia Vicenzi et al.
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Differential Diagnoses of Inclusion Body Myositis

Neurologic Clinics
2020 | Journal article
DOI: 10.1016/J.NCL.2020.03.014
WOSUID: WOS:000566784500017
Contributors: Vivekanandam, Vinojini; Bugiardini, Enrico; Merve, Ashirwad; Parton, Matthew; Morrow, Jasper M.; Hanna, Michael G.; Machado, Pedro M.
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DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study

The Lancet Child & Adolescent Health
2020 | Journal article
DOI: 10.1016/S2352-4642(19)30342-6
WOSUID: WOS:000509354100015
Contributors: Pickles, Jessica C.; Fairchild, Amy R.; Stone, Thomas J.; Brownlee, Lorelle; Merve, Ashirwad; Yasin, Shireena A.; Avery, Aimee; Ahmed, Saira W.; Ogunbiyi, Olumide; Zapata, Jamie Gonzalez et al.
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Genetic alterations in advanced-stage paediatric central nervous system tumours: a next-generation sequencing study

Neuropathology and Applied Neurobiology
2020 | Journal article
WOSUID: WOS:000513987400011
Contributors: Smolicz, I.; Pickles, J. C.; Stone, T. J.; Fairchild, A. R.; Ahmed, S. W.; Chalker, J.; Dryden, C.; Zapata, J. Gonzalez; Herron, B.; Joshi, A. R. et al.
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Multisystem mitochondrial disease caused by a rare m.10038G&gt;A mitochondrial tRNA<SUP>Gly</SUP> (<i>MT-TG</i>) variant

Neurology Genetics
2020 | Journal article
DOI: 10.1212/NXG.0000000000000413
WOSUID: WOS:000532368400017
Contributors: Poole, Olivia, V; Horga, Alejandro; Hardy, Steven A.; Bugiardini, Enrico; Woodward, Cathy E.; Hargreaves, Iain P.; Merve, Ashirwad; Quinlivan, Rosaline; Taylor, Robert W.; Hanna, Michael G. et al.
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C-MYC OVEREXPRESSION INDUCES CHOROID PLEXUS PAPILLOMAS THROUGH A T-CELL MEDIATED INFLAMMATORY MECHANISM

Neuro-Oncology
2019 | Journal article
WOSUID: WOS:000473243700245
Contributors: Merve, Ashirwad; Zhang, Xinyu; Pomella, Nicola; Dumas, Anaelle; Marino, Silvia
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c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism (vol 7, 95, 2019)

Acta Neuropathologica Communications
2019 | Journal article
DOI: 10.1186/S40478-019-0835-Y
WOSUID: WOS:000497384100002
Contributors: Merve, Ashirwad; Zhang, Xinyu; Pomella, Nicola; Acquati, Serena; Hoeck, Joerg D.; Dumas, Anaelle; Rosser, Gabriel; Li, Yichen; Jeyapalan, Jennie; Vicenzi, Silvia et al.
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CHOROID PLEXUS PAPILLOMAS ARE INDUCED BY C-MYC OVEREXPRESSION IN THE CHOROID PLEXUS VIA A T-CELL INFLAMMATORY MECHANISM

Neuro-Oncology
2019 | Journal article
DOI: 10.1093/NEUONC/NOZ167.040
WOSUID: WOS:000491241200042
Contributors: Merve, Ashirwad; Zhang, Xinyu; Pomella, Nicola; Acquati, Serena; Hoeck, Joerg; Dumas, Anaelle; Rosser, Gabriel; Li, Yichen; Jeyapalan, Jennie; Vicenzi, Silvia et al.
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DNA methylation profiling in paediatric CNS tumours

Neuropathology and Applied Neurobiology
2019 | Journal article
WOSUID: WOS:000460348400056
Contributors: Pickles, J. C.; Stone, T. J.; Brownlee, L.; Merve, A.; Yasin, S.; Wilku, L.; Kristiansen, M.; Hargrave, D.; Chalker, J.; Jacques, T. S.
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Intraosseous Thoracic Schwannoma: Case Report and Review of the Literature

World Neurosurgery
2019 | Journal article
DOI: 10.1016/J.WNEU.2019.06.222
WOSUID: WOS:000488248200197
Contributors: Zaidman, Nathalie; Merve, Ashirwad; Russo, Vittorio
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Recurrent Langerhans cell histiocytosis at the site of prior craniotomy: case report

Journal of Neurosurgery: Pediatrics
2019 | Journal article
DOI: 10.3171/2019.6.PEDS19286
WOSUID: WOS:000500271300014
Contributors: Iqbal, M. Omar; Merve, Ashirwad; Galea, Nathalie; Aquilina, Kristian
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Supplementary data for DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population based study

2019 | Journal article
DOI: 10.5522/04/9918575
Contributors: Jessica Pickles; Amy Fairchild; Tom Stone; ; ; ; Aimee Avery; ; ; Jamie Gonzalez Zapata et al.
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Ashirwad Merve

The Biology Of Paediatric Central Nervous System Tumours At Post-Mortem

Journal of Neuropathology & Experimental Neurology
2019 | Journal article
WOSUID: WOS:000472806000145
Contributors: Smolicz, Izabella; Fairchild, Amy; Pickles, Jessica; Stone, Thomas; Chalker, Jane; Zapata, Jamie Gonzalez; Wilkhu, Lisa; Yasin, Shireena; Merve, Ashirwad; Hargrave, Darren et al.
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USEFULNESS OF CONCOMITANT PERIPHERAL NERVE AND MUSCLE BIOPSY

Journal of Neurology, Neurosurgery & Psychiatry
2019 | Journal article
DOI: 10.1136/JNNP-2019-ABN-2.197
WOSUID: WOS:000522138000221
Contributors: Cooper, Rebecca; Bunting, Eva; Jaunmuktane, Zane; Merve, Ashirwad; Rosser, Alex; laura, MatilDe; Manji, Hadi; Reilly, Mary M.; Lunn, Mike P.; Carr, Aisling S.
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c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism

Acta Neuropathologica Communications
2019-12 | Journal article
DOI: 10.1186/s40478-019-0739-x
Part of ISSN: 2051-5960
Contributors: Ashirwad Merve; Xinyu Zhang; Nicola Pomella; Serena Acquati; Joerg D. Hoeck; Anaelle Dumas; Gabriel Rosser; Yichen Li; Jennie Jeyapalan; Silvia Vicenzi et al.
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Integrated phenotype–genotype approach in diagnosis and classification of common central nervous system tumours

Histopathology
2019-09 | Journal article
DOI: 10.1111/his.13849
Contributors: Ashirwad Merve; Thomas O Millner; Silvia Marino
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c-Myc overexpression induces choroid plexus tumours and modulates inflammatory pathways

Neuropathology and Applied Neurobiology
2018 | Journal article
WOSUID: WOS:000426519200019
Contributors: Merve, A.; Zhang, X.; Dumas, A.; Acquati, S.; Jeyapalan, J.; Sabo, A.; Amati, B.; Behrens, A.; Marino, S.
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Hyaline astrocytic inclusions in paediatric onset intractable epilepsy

Neuropathology and Applied Neurobiology
2018 | Journal article
WOSUID: WOS:000426519200050
Contributors: Merve, A.; Nagaraju, S.
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Peer review (19 reviews for 5 publications/grants)

Review activity for Cytopathology. (4)
Review activity for European Journal of Immunology (2)
Review activity for Histopathology. (6)
Review activity for International journal of experimental pathology. (3)
Review activity for Neuropathology & applied neurobiology. (4)
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