
Professor Thalia Eley PhD
Professor of Developmental Behavioural Genetics
- Head of Department, Social, Genetic & Developmental Psychiatry Centre
Research interests
- Mental Health
Biography
Thalia Eley is Professor of Developmental Behavioural Genetics and Head of Department in the Social, Genetic & Developmental Psychiatry (SGDP) Centre at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King’s College London. She leads the Emotional Development, Intervention and Treatment (EDIT) lab, and her work focuses on the interplay between genetic and environmental factors in the development and treatment of anxiety and depression.
For her undergraduate degree, she studied Social and Political Sciences, with a focus on psychology, at Trinity College Cambridge. She undertook her PhD at the Institute of Child Health, University College London, where she studied the role of genetic and environmental influences on depression and anxiety in young people. After two MRC research fellowships, she became a member of academic staff at the Institute of Psychiatry, Psychology & Neuroscience and was promoted to Professor in 2013.
Her work is highly interdisciplinary using both the twin design and molecular genetic approaches, and drawing on cognitive, clinical and developmental psychology. She has written over 140 empirical papers and received numerous awards including the Spearman Medal from the British Psychological Society, the Lilly-Molecular Psychiatry Award, and most recently the James Shields Lifetime Achievement Award from the International Society for Twin Studies. She is one of the Chairs of the Psychiatric Genomics Consortium Anxiety Group.
Professor Eley is passionate about enabling early career researchers and was Chair of the Research and Innovation Committee for over five years, developing and leading numerous initiatives aimed at supporting this group. She is keen to see greater diversity in those conducting, and taking part, in scientific research.
Research interests
- Finding ways in which genetic approaches can inform psychological practice as well as theory.
- Using molecular genetics to explore the role of specific genetic markers in the development of anxiety and depression, and as predictors of psychological therapies response for these conditions.
- Why anxiety and depression tend to run in families, and whether this is due to sharing home life or whether it is due to sharing genes.
With her close colleague Professor Gerome Breen, head of the NIHR Maudsley BioResource Centre, she is leading Genetics Links to Anxiety and Depression (GLAD) Study. Watch a video of them describing the purpose of this study here, and an animation about the study here. She is particularly excited about this area of work as it has the potential to be useful in making clinical decisions.
Thalia is the Director of the Twins Early Development Study (TEDS), the largest longitudinal twin birth cohort in the UK. As the twins reach their mid-twenties, the team is particularly excited about recruiting the next generation into the Children of TEDS (CoTEDS) Study.
Teaching
- SGDP Education lead
- Assessment Sub-Board Chair for SGDP DEV-PP Masters programme
- Teaching on genetics of anxiety, depression and treatment response
- Grant writing training
Expertise and public engagement
The EDIT lab runs a blog. The GLAD Study participants are recruited via the media and social media, so the team has written numerous articles (and had lots of articles written about them), as well as featuring on TV and traditional media.
Her team has worked closely with many charities (e.g. MIND) and with the British Psychological Society and Royal College of Psychiatrists all of whom supported and promoted the GLAD study.
Professor Eley has written blogs for Mental Elf and have spoken at Pint of Science twice.
She has given many lecturers about her work:
- Inaugural lecture (Autumn 2013) here, in which she gave an overview of the work she undertook from her PhD in the 1990s until 2013 when she became a professor.
- Therapy genetics lecture (Spring 2017) here, as part of the Stockholm Psychiatry lecture series.
- This lecture is a brief update of the work of the Psychiatric Genetics Consortium Anxiety group (Spring 2020).
Awards
- 2021 Fellow of the Academy of Medical Sciences
- 2019 King's University Research Project of the year (GLAD Study)
- 2017 James Shields Lifetime Achievement Award from the International Society for Twin Studies
- 2017 King's Graduate School IoPPN Supervisory Excellence Award
- 2004 Lilly-Molecular Psychiatry Award
- 2002 British Psychological Society Spearman Medal
A network analysis of body dysmorphic and obsessive-compulsive symptoms among individuals with and without exposure to trauma.
Song, L., Veale, D., Eley, T. & Krebs, G., 1 May 2025, In: Journal of affective disorders. 376, p. 206-215 10 p.Research output: Contribution to journal › Article › peer-review
Common Genetic and Environmental Contributions to Anxiety Sensitivity, Anxiety, and Cognitive Symptoms of Eating Disorders in Adolescence
Smail-Crevier, R., Breen, G., Eley, T. C. & Rappaport, L. M., 1 Feb 2025, In: Research on Child and Adolescent Psychopathology. 53, 2, p. 193-205 13 p.Research output: Contribution to journal › Article › peer-review
Depression symptom-specific genetic associations in clinically diagnosed and proxy case Alzheimer’s disease
Gilchrist, L., Spargo, T. P., Green, R. E., Coleman, J. R. I., Howard, D. M., Thorp, J. G., Adey, B. N., Lord, J., Davies, H. L., Mundy, J., ter Kuile, A. R., Davies, M. R., Hübel, C., Bristow, S., Lee, S. H., Rogers, H., Curtis, C., Kakar, S., Malouf, C. M. & Kalsi, G. & 14 others, Arathimos, R., Corbett, A., Ballard, C., Brooker, H., Creese, B., Aarsland, D., Hampshire, A., Velayudhan, L., Eley, T. C., Breen, G., Iacoangeli, A., Kõks, S., Lewis, C. M. & Proitsi, P., Feb 2025, In: Nature Mental Health . 3, 2, p. 212-228 17 p., 160.Research output: Contribution to journal › Article › peer-review
Genetic overlap between functional impairment and depression and anxiety symptom severity: Evidence from the GLAD Study
Skelton, M., Mundy, J., ter Kuile, A., Adey, B., Armour, C., Buckman, J. E. J., Coleman, J., Davies, M., Hirsch, C., Hotopf, M., Jones, I. R., Kalsi, G., Krebs, G., Lee, S.-H., Lin, Y., M. McIntosh, A., Peel, A., Rayner, C., Rimes, K. & Smith, D. J. & 6 others, Thompson, K., Veale, D., Walters, J., Hübel, C., Breen, G. & Eley, T., 17 Jun 2025, (Accepted/In press) In: Psychological Medicine.Research output: Contribution to journal › Article › peer-review
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes
Assary, E., Coleman, J., Hemani, G., Van De Weijer, M., Howe, L. J., Palviainen, T., Grasby, K. L., Ahlskog, R., Nygaard, M., Cheesman, R., Lim, K., Reynolds, C. A., Ordoñana, J. R., Colodro-Conde, L., Gordon, S. G., Madrid-Valero, J. J., Thalamuthu, A., Hottenga, J.-J., Mengel-From, J. & Armstrong, N. J. & 32 others, Sachdev, P., Lee, T., Brodaty, H., Trollor, J. N., Wright, M. J., Ames, D., Catts, V. S., Latvala, A., Vuoksimaa, E., Mallard, T. T., Harden, K. P., Tucker-drob, E. M., Oskarsson, S., Hammond, C. J., Christensen, K., Taylor, M. J., Lundström, S., Larsson, H., Karlsson, R., Pedersen, N. L., Mather, K. A., Medland, S. E., Boomsma, D. I., Martin, N. G., Plomin, R., Bartels, M., Lichtenstein, P., Kaprio, J., Eley, T., Davies, N. M., Munroe, P. B. & Keers, R., 10 Jun 2025, In: Nature Human Behaviour.Research output: Contribution to journal › Article › peer-review
Heritability of generalized anxiety stability: a longitudinal twin study among young adults
Funk (Student), J., Morneau-Vaillancourt, G., Palaiologou, E. & Eley, T., 30 Jun 2025, In: Psychological medicine. 55, e180.Research output: Contribution to journal › Article › peer-review
Investigating the genetic relationship between depression symptoms and Alzheimer’s Disease in clinically diagnosed and proxy cases
Gilchrist, L., Coleman, J., Howard, D., Adey, B., Davies, H. L., Mundy, J., ter Kuile, A., Davies, M., Bristow, S., Lee, S., Rogers, H., Curtis, C., Kalsi, G., Arathimos, R., Eley, T., Breen, G., Iacoangeli, A., Lewis, C. & Proitsi, P., 15 Jan 2025, In: Nature Mental Health .Research output: Contribution to journal › Article › peer-review
Peer problems and prosocial behaviours across development: associations with anxiety and depression in emerging adulthood
Morneau-Vaillancourt, G., Kwong, A. S. F., Thompson, K. V., Skelton, M., Thompson, E. J., Assary, E., Lockhart, C., Oginni, O. A., Palaiologou, E., McGregor, T., Arseneault, L. & Eley, T., 15 Jul 2025, In: Journal of affective disorders. 381, p. 360-371 12 p.Research output: Contribution to journal › Article › peer-review
Self-report measures of fear learning and extinction and their association with internet-based cognitive behavioural therapy outcome
McGregor, T., Carr, E., Davies, M., Kerr, T., Krebs, G., Purves, K., Skelton, M., Breen, G., Hirsch, C. & Eley, T., Apr 2025, In: Behaviour Research and Therapy. 187, 104705.Research output: Contribution to journal › Article › peer-review
Single-Item Patient-Rated Helpfulness and Improvement as an Alternative to Standardized Questionnaires for Establishing Anxiety and Depression Treatment Efficacy
Sewerynek, P., Wagner, C., McGregor, T., Skelton, M. & Eley, T., 10 Mar 2025, (Accepted/In press) In: Psychological Assessment.Research output: Contribution to journal › Article › peer-review
Software Application Profile: TIDAL – Tool to Implement Developmental Analysis of Longitudinal data
Kwong, A., Edmondson-Stait, A., Xu, E., Thompson, E. J., Parker, R. M. A., Elhakeem, A., Romaniuk, L., Pearson, R. M., Tilling, K., Eley, T., McIntosh, A. M. & Whalley, H., 6 Jul 2025, In: International Journal of Epidemiology.Research output: Contribution to journal › Article › peer-review
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell-types and pharmacotherapies
MDD Working Group of the Psychiatric Genomics Consortium, 6 Feb 2025, In: Cell. 188, 3, p. 640-652.e9Research output: Contribution to journal › Article › peer-review
UK Longitudinal Linkage Collaboration (UK LLC): The National Trusted Research Environment for Longitudinal Research
Boyd, A., Evans, K., Turner, E., Flaig, R., Oakley, J., Campbell, K., Thomas, R., McLachlan, S., Crane, M., Breen, G., Bristow, S., Das-Munshi, J., Eley, T., Fisher, H., Lockhart, C., Steves, C. & Chaturvedi, N., 17 Feb 2025, In: International Journal of Population Data Science. 10, 1, 06.Research output: Contribution to journal › Article › peer-review
Use of the FLARe Smartphone App in a Trauma-Exposed Sample: A Feasibility Study
Bountress, K. E., Latourrette, C., Purves, K. L., McGregor, T., Lasko, E., Dagher, A., Dick, D. M. & Eley, T., 1 Apr 2025, (Accepted/In press) In: Journal of Addictions Nursing.Research output: Contribution to journal › Article › peer-review
Causal and common risk pathways linking childhood maltreatment to later intimate partner violence victimization
Pezzoli, P., Pingault, J.-B., Eley, T. C., McCrory, E. & Viding, E., 1 Nov 2024, In: Molecular Psychiatry.Research output: Contribution to journal › Article › peer-review
Developmental Trajectories of Child and Adolescent Emotional Problems: associations with early adult alcohol use behaviors
Chen, T., Oginni, O. A., Hannigan, L. J., Eley, T. C., Maggs, J. L., Linden‐Carmichael, A. N. & Neiderhiser, J. M., 17 Dec 2024, In: Journal of child psychology and psychiatry. 66, 1, p. 85-97Research output: Contribution to journal › Article › peer-review
Genetics of environmental sensitivity and its association with variations in emotional problems, autistic traits, and wellbeing
Assary, E., Oginni, O. A., Morneau-Vaillancourt, G., Krebs, G., Palaiologou, E., Lockhart, C., Ronald, A. & Eley, T., 3 Mar 2024, In: Molecular Psychiatry. 29, 8, p. 2438-2446 9 p.Research output: Contribution to journal › Article › peer-review
Patterns of sub‐optimal change following CBT for childhood anxiety
Bertie, L., Arendt, K., Coleman, J. R. I., Cooper, P., Creswell, C., Eley, T. C., Hartman, C., Heiervang, E. R., In‐Albon, T., Krause, K., Lester, K. J., Marin, C. E., Nauta, M., Rapee, R. M., Schneider, S., Schniering, C., Silverman, W. K., Thastum, M., Thirlwall, K. & Waite, P. & 2 others, Wergeland, G. J. & Hudson, J. L., 30 May 2024, In: Journal of child psychology and psychiatry. 65, 12, p. 1612-1623Research output: Contribution to journal › Article › peer-review
Perinatal risk factors and subclinical hypomania: A prospective community study
Gonzalez-Calvo, I., Ronald, A., Shakoor, S., Taylor, M. J., Eley, T. & Hosang, G. M., 1 Oct 2024, In: Journal of affective disorders. p. 885-892Research output: Contribution to journal › Article › peer-review
Polygenic influences on networks of psychopathology symptoms: Unweaving the web
Piazza, G., Allegrini, A., Eley, T., Epskamp, S., Fried, E. I., Isvoranu, A.-M., Roiser, J. P. & Pingault, J.-B., 27 Mar 2024, (Accepted/In press) In: JAMA Psychiatry.Research output: Contribution to journal › Article › peer-review
Polygenic Scores and Networks of Psychopathology Symptoms
Piazza, G. G., Allegrini, A. G., Eley, T. C., Epskamp, S., Fried, E., Isvoranu, A.-M., Roiser, J. P. & Pingault, J.-B., 12 Jun 2024, (E-pub ahead of print) In: JAMA Psychiatry. 81, 9, p. 902-910Research output: Contribution to journal › Article › peer-review
Predicting remission following CBT for childhood anxiety disorders: a machine learning approach
Bertie, L.-A., Quiroz, J. C., Berkovsky, S., Arendt, K., Bögels, S., Coleman, J. R. I., Cooper, P., Creswell, C., Eley, T. C., Hartman, C., Fjermestadt, K., In-Albon, T., Lavallee, K., Lester, K. J., Lyneham, H. J., Marin, C. E., McKinnon, A., McLellan, L. F., Meiser-Stedman, R. & Nauta, M. & 10 others, Rapee, R. M., Schneider, S., Schniering, C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J., Wuthrich, V. & Hudson, J. L., 17 Dec 2024, (E-pub ahead of print) In: Psychological Medicine. p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
Using Bifactor Twin Modeling to Assess the Genetic and Environmental Dimensionality of Adult ADHD Symptoms
Knyspel, J., Morneau-Vaillancourt, G. & Eley, T. C., 30 Oct 2024, In: Behavior Genetics. 55, p. 1-11Research output: Contribution to journal › Article › peer-review
A cross-lagged twin study of emotional symptoms, social isolation, and peer victimisation from early adolescence to emerging adulthood
Morneau-Vaillancourt, G., Oginni, O., Assary, E., Krebs, G., Thompson, E., Palaiologou, E., Lockhart, C., Arseneault, L. & Eley, T., Nov 2023, In: Journal of Child Psychiatry & Psychology. 64, 11, p. 1569-1582 14 p.Research output: Contribution to journal › Article › peer-review
A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents
Peel, A., Oginni, O. A., Assary, E., Krebs, G., Lockhart, C., McGregor, T., Palaiologou, E., Ronald, A., Danese, A. & Grant, T. E., 13 Feb 2023, In: Journal of Child Psychology and Psychiatry.Research output: Contribution to journal › Article › peer-review
A multivariate twin study of the genetic association between present moment attention and subjective wellbeing
Brown, K. W., Aliev, F., Eley, T., Dick, D. M. & Sawyers, C., 14 Oct 2023, In: Scientific Reports.Research output: Contribution to journal › Article › peer-review
Bidirectional causal associations between same-sex attraction and psychological distress: Testing moderation and mediation effects
Oginni, O. A., Lim, K., Rahman, Q., Jern, P., Grant, T. E. & Rijsdijk, F., Mar 2023, In: Behavior Genetics. 53, 2, p. 118–131 14 p.Research output: Contribution to journal › Article › peer-review
Differential susceptibility theory: might it help in understanding and treating mental health problems in youth?
Assary, E., Krebs, G. & Eley, T., 7 Jul 2023, In: Journal of Child Psychology and Psychiatry. 64, 8, p. 1104-1114 11 p.Research output: Contribution to journal › Review article › peer-review
Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies
Waszczuk, M. A., Jonas, K. G., Bornovalova, M., Breen, G., Bulik, C. M., Docherty, A. R., Eley, T. C., Hettema, J. M., Kotov, R., Krueger, R. F., Lencz, T., Li, J. J., Vassos, E. & Waldman, I. D., 4 Jul 2023, (E-pub ahead of print) In: Molecular Psychiatry. 11 p.Research output: Contribution to journal › Article › peer-review
Evidence for distinct genetic and environmental influences on fear acquisition and extinction
Purves, K. L., Krebs, G., McGregor, T., Constantinou, E., Lester, K., Barry, T., Craske, M. G., Young, K., Breen, G. & Eley, T. C., Feb 2023, In: Psychological Medicine.Research output: Contribution to journal › Article › peer-review
Factors associated with anxiety disorder comorbidity
Davies, M. R., Glen, K., Mundy, J., Adey, B., Armour, C., Assary, E., Coleman, J., Goldsmith, K., Hirsch, C., Hotopf, M., Hübel, C., Jones, I., Kalsi, G., Krebs, G., McIntosh, A. M., Morneau-Vaillancourt, G., Peel, A., Purves, K., Lee, S. & Skelton, M. & 7 others, Smith, D. J., Veale, D., Walters, J., Young, K., Zvrskovec, J., Breen, G. & Grant, T. E., 15 Feb 2023, In: Journal of Affective Disorders. 323, p. 280-291 12 p.Research output: Contribution to journal › Article › peer-review
Genetic decomposition of the heritable component of reported childhood maltreatment
ter Kuile, A., Hübel, C., Cheesman, R., Coleman, J., Peel, A., Levey, D. F., Stein, M. B., Gelernter, J., Rayner, C., Eley, T. & Breen, G., 6 Jun 2023, In: Biological Psychiatry: Global Open Science. 3, 4, p. 716-724 9 p.Research output: Contribution to journal › Article › peer-review
Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder
Mundy, J., Hübel, C., Adey, B., Davies, H., Davies, M. R., Coleman, J., Hotopf, M., Kalsi, G., Lee, S. H., M. McIntosh, A., Rogers, H., Eley, T., Murray, R., Vassos, E. & Breen, G., 1 Oct 2023, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 192, 7-8, p. 147-160 14 p.Research output: Contribution to journal › Article › peer-review
Introducing the Fear Learning and Anxiety Response (FLARe) app and web portal for the remote delivery of fear conditioning experiments
McGregor, T., Purves, K., Barry, T., Constantinou, E., Craske, M. G., Breen, G., Young, K. & Eley, T., Sept 2023, In: Behaviour Research Methods.Research output: Contribution to journal › Article › peer-review
Networks of Neurodevelopmental Traits, Socioenvironmental Factors, Emotional Dysregulation in Childhood, and Depressive Symptoms Across Development in Two U.K. Cohorts
Farhat, L. C., Blakey, R., Davey Smith, G., Fujita, A., Shephard, E., Stergiakouli, E., Eley, T. C., Thapar, A. & Polanczyk, G. V., 1 Oct 2023, In: American Journal of Psychiatry. 180, 10, p. 755-765Research output: Contribution to journal › Article › peer-review
Predicting prognosis for adults with depression using individual symptom data: a comparison of modelling approaches
Buckman, J. E. J., Cohen, Z. D., O'Driscoll, C., Fried, E. I., Saunders, R., Ambler, G., DeRubeis, R. J., Gilbody, S., Hollon, S. D., Kendrick, T., Watkins, E., Eley, T. C., Peel, A. J., Rayner, C., Kessler, D., Wiles, N., Lewis, G. & Pilling, S., Jan 2023, In: Psychological Medicine. p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
Research priorities in psychiatric genetic counselling: how to talk to children and adolescents about genetics and psychiatric disorders
Mundy, J., Davies, H. L., Radu, M., Austin, J., Vassos, E., Eley, T. C., Breen, G. & Moldovan, R., Mar 2023, In: European Journal of Human Genetics. 31, 3, p. 262-264 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Seeking help for mental health during the COVID-19 pandemic: A longitudinal analysis of adults’ experiences with digital technologies and services
Parsons, C. E., Purves, K. L., Davies, M. R., Mundy, J., Bristow, S., Eley, T. C., Breen, G., Hirsch, C. R. & Young, K. S., 1 Dec 2023, In: PLOS digital health. 2, 12, e0000402.Research output: Contribution to journal › Article › peer-review
Sociodemographic, mental health, and physical health factors associated with participation within re-contactable mental health cohorts: an investigation of the GLAD Study
Bright, S. J., Hübel, C., Young, K. S., Bristow, S., Peel, A. J., Rayner, C., Mundy, J., Palmos, A. B., Purves, K. L., Kalsi, G., Armour, C., Jones, I. R., Hotopf, M., McIntosh, A. M., Smith, D. J., Walters, J. T. R., Rogers, H. C., Thompson, K. N., Adey, B. N. & Monssen, D. & 9 others, Kakar, S., Malouf, C. M., Hirsch, C., Glen, K., Kelly, E. J., Veale, D., Eley, T. C., Breen, G. & Davies, M. R., Dec 2023, In: BMC Psychiatry. 23, 1, 542.Research output: Contribution to journal › Article › peer-review
The conditional associations between neurodevelopmental traits, social-environmental stressors, and emotional dysregulation in childhood and depressive symptoms over development: a Bayesian multivariate analysis of two UK cohorts
Farhat, L. C., Farhat, L. C., Smith, G. D., Fujita, A., Shephard, E., Stergiakouli, E., Eley, T., Thapar, A. & Polanczyk, G., 24 May 2023, (Accepted/In press) In: Journal of Psychiatry.Research output: Contribution to journal › Article › peer-review
The network structure of mania symptoms differs between people with and without binge eating
Davies, H. L., Peel, A. J., Mundy, J., Monssen, D., Kakar, S., Davies, M. R., Adey, B. N., Armour, C., Kalsi, G., Lin, Y., Marsh, I., Rogers, H. C., Walters, J. T. R., Herle, M., Glen, K., Malouf, C. M., Kelly, E. J., Eley, T. C., Treasure, J. & Breen, G. & 1 others, Hübel, C., Nov 2023, In: Bipolar Disorders. 25, 7, p. 592-607 16 p.Research output: Contribution to journal › Article › peer-review
The p factor of psychopathology and personality in middle childhood: Genetic and gestational risk factors
Gjerde, L. C., Eilertsen, E. M., McAdams, T. A., Cheesman, R., Moffitt, T. E., Caspi, A., Eley, T. C., Roysamb, E., Rosenström, T. H. & Ystrom, E., 10 Jul 2023, In: Psychological Medicine. 53, 9, p. 4275-4285 11 p.Research output: Contribution to journal › Article › peer-review
The p factor of psychopathology and personality in middle childhood: Genetic and gestational risk factors - Corrigendum
Gjerde, L. C., Eilertsen, E. M., McAdams, T. A., Cheesman, R., Moffitt, T. E., Caspi, A., Eley, T. C., Røysamb, E., Rosenström, T. H. & Ystrom, E., 1 Jul 2023, In: Psychological Medicine. 53, 9, p. 4303-4304 2 p.Research output: Contribution to journal › Article › peer-review
The relationship between weight-related indicators and depressive symptoms during adolescence and adulthood: results from two twin studies
Thompson, E. J., Krebs, G., Zavos, H., Steves, C. & Eley, T., 31 Aug 2023, (E-pub ahead of print) In: Psychological medicine.Research output: Contribution to journal › Article › peer-review
The relationship between weight-related indicators and depressive symptoms during adolescence and adulthood: results from two twin studies
Thompson, E. J., Krebs, G., Zavos, H., Steves, C. & Eley, T., 31 Aug 2023, In: Psychological medicine.Research output: Contribution to journal › Article › peer-review
The United Kingdom Eating Disorders Genetics Initiative
Monssen, D., Davies, H., Kakar, S., Curzons, S., Davies, M., Kelly, E., Ahmad, Z., Bradley, J. R., Bright, S. J., Coleman, J., Glen, K., Hotopf, M., ter Kuile, A., Malouf, M., Kalsi, G., Kingston, N., McAtarsney-Kovacs, M., Mundy, J., Peel, A. & Palmos, A. & 12 others, Rogers, H., Skelton, M., Adey, B., Lee, S.-H., Virgo, H., Quinn, T., Price, T., Zvrskovec, J., Eley, T., Treasure, J., Hübel, C. & Breen, G., 16 Aug 2023, In: International Journal of Eating Disorders. p. 1-15 15 p.Research output: Contribution to journal › Article › peer-review
Trajectories of depression and anxiety symptom severity during psychological therapy for common mental health problems
Skelton, M., Carr, E., Buckman, J. E. J., Davies, M. R., Goldsmith, K., Hirsch, C. R., Peel, A. J., Rayner, C., Rimes, K., Saunders, R., Wingrove, J., Breen, G. & Grant, T. E., 25 Sept 2023, In: Psychological Medicine. 53, 13, p. 6183-6193 11 p.Research output: Contribution to journal › Article › peer-review
Trajectories of depression symptoms, anxiety symptoms and functional impairment during internet-enabled cognitive-behavioural therapy
Skelton, M., Catarino, A., Brown, S., Carr, E., Davies, M., Peel, A. J., Rayner, C., Breen, G. & Eley, T., 12 Aug 2023, (Accepted/In press) In: Behaviour Research and Therapy.Research output: Contribution to journal › Article › peer-review
Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties.
Lockhart, C., Bright, J., Ahmadzadeh, Y., Breen, G., Bristow, S., Boyd, A., Downs, J., Hotopf, M., Palaiologou, E., Rimfeld, K., Maxwell, J., Malachini, M., McAdams, T. A., McMillan, A., Plomin, R. & Eley, T. C., 30 Mar 2023, In: JCPP Advances.Research output: Contribution to journal › Article › peer-review
Comparison of symptom-based versus self-reported diagnostic measures of anxiety and depression disorders in the GLAD and COPING cohorts
Davies, M. R., Buckman, J. E. J., Adey, B. N., Armour, C., Bradley, J. R., Curzons, S. C. B., Davies, H. L., Davis, K. A. S., Goldsmith, K. A., Hirsch, C. R., Hotopf, M., Hübel, C., Jones, I. R., Kalsi, G., Krebs, G., Lin, Y., Marsh, I., McAtarsney-Kovacs, M., McIntosh, A. M. & Mundy, J. & 12 others, Monssen, D., Peel, A. J., Rogers, H. C., Skelton, M., Smith, D. J., Ter Kuile, A., Thompson, K. N., Veale, D., Walters, J. T. R., Zahn, R., Breen, G. & Eley, T. C., Jan 2022, In: Journal of Anxiety Disorders. 85, 102491.Research output: Contribution to journal › Article › peer-review
Research

TEDS: Twins Early Development Study
The Twin Early Development Study (TEDS) is one of the leading large-scale twin studies in the world. Starting in 1994, it has followed twins born in England and Wales throughout their childhood and adolescence and has now continued into early adulthood.

The Emotional Development, Interventions and Treatment (EDIT) Lab
The EDIT lab is led by Prof Thalia Eley and consists of post doctoral researchers, PhD students, and both undergraduate and masters students. We study genetic and environmental influences on the development and treatment of anxiety and depression. We are based at the SGDP Centre at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London.

GLAD: Genetic Links to Anxiety and Depression
The GLAD Study is the largest anxiety and depression project ever undertaken. It was launched in September 2018.
Project status: Ongoing

Children of TEDS (CoTEDS) Study
The aim of this project is to explore the origins of the development of emotional disorders.
Project status: Ongoing

FLARe: Fear Learning and Anxiety Response
FLARe aims to model the processes underlying the development, maintenance and treatment of anxiety disorders, and post-treatment relapse.
Project status: Ongoing

G1219: Genesis 1219
G1219 is a longitudinal study that aims to examine the interplay between genes and the environment on the development of anxiety and depression over time.
Project status: Completed

Repeated Assessment of Mental health in Pandemics (RAMP)
The Repeated Assessment of Mental health in Pandemics (RAMP) study is a research project assessing the effect of COVID-19 on the mental health and wellbeing of the population.

Learning Effective New Strategies (LENS)
LENS (Learning Effective New Strategies) is a digital therapy shown to reduce anxiety and depression.
Project status: Ongoing
News
Professor Thalia Eley elected a Fellow of the British Academy
Professor Eley joins 92 new Fellows welcomed to the prestigious British Academy, in recognition of scholarly distinction in the humanities and social sciences.

Largest twin study explores whether the environment affects people differently depending on their genes
Researchers at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London, University College London, Queen Mary University of...

£4.8 million Wellcome funding to predict outcomes following anxiety treatment
Wellcome has awarded over £4.8m for researchers to predict individual outcomes following psychological treatments for anxiety, and to identify genetic and...

UK Longitudinal Linkage Collaboration awarded £6.4m
New funding from MRC/ESRC will allow partnership between leading UK longitudinal studies, including King’s-led studies GLAD and EDGI UK will enable...

Professor Thalia Eley elected as Fellow of the Academy of Medical Sciences
Professor Eley is one of 50 new Fellows to be elected to the prestigious Academy of Medical Sciences

Twins Early Development Study receives £3.2million funding from MRC
Successful grant renewal from Medical Research Council (MRC) will fund pioneering Twin Early Development Study until 2025.

Features
Exploring research into anxiety disorders this Mental Health Awareness Week
This year, Mental Health Awareness Week took place Monday 15 - Sunday 21 June, following the theme ‘anxiety’. Anxiety is a normal emotion in us all, but...

A network analysis of body dysmorphic and obsessive-compulsive symptoms among individuals with and without exposure to trauma.
Song, L., Veale, D., Eley, T. & Krebs, G., 1 May 2025, In: Journal of affective disorders. 376, p. 206-215 10 p.Research output: Contribution to journal › Article › peer-review
Common Genetic and Environmental Contributions to Anxiety Sensitivity, Anxiety, and Cognitive Symptoms of Eating Disorders in Adolescence
Smail-Crevier, R., Breen, G., Eley, T. C. & Rappaport, L. M., 1 Feb 2025, In: Research on Child and Adolescent Psychopathology. 53, 2, p. 193-205 13 p.Research output: Contribution to journal › Article › peer-review
Depression symptom-specific genetic associations in clinically diagnosed and proxy case Alzheimer’s disease
Gilchrist, L., Spargo, T. P., Green, R. E., Coleman, J. R. I., Howard, D. M., Thorp, J. G., Adey, B. N., Lord, J., Davies, H. L., Mundy, J., ter Kuile, A. R., Davies, M. R., Hübel, C., Bristow, S., Lee, S. H., Rogers, H., Curtis, C., Kakar, S., Malouf, C. M. & Kalsi, G. & 14 others, Arathimos, R., Corbett, A., Ballard, C., Brooker, H., Creese, B., Aarsland, D., Hampshire, A., Velayudhan, L., Eley, T. C., Breen, G., Iacoangeli, A., Kõks, S., Lewis, C. M. & Proitsi, P., Feb 2025, In: Nature Mental Health . 3, 2, p. 212-228 17 p., 160.Research output: Contribution to journal › Article › peer-review
Genetic overlap between functional impairment and depression and anxiety symptom severity: Evidence from the GLAD Study
Skelton, M., Mundy, J., ter Kuile, A., Adey, B., Armour, C., Buckman, J. E. J., Coleman, J., Davies, M., Hirsch, C., Hotopf, M., Jones, I. R., Kalsi, G., Krebs, G., Lee, S.-H., Lin, Y., M. McIntosh, A., Peel, A., Rayner, C., Rimes, K. & Smith, D. J. & 6 others, Thompson, K., Veale, D., Walters, J., Hübel, C., Breen, G. & Eley, T., 17 Jun 2025, (Accepted/In press) In: Psychological Medicine.Research output: Contribution to journal › Article › peer-review
Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes
Assary, E., Coleman, J., Hemani, G., Van De Weijer, M., Howe, L. J., Palviainen, T., Grasby, K. L., Ahlskog, R., Nygaard, M., Cheesman, R., Lim, K., Reynolds, C. A., Ordoñana, J. R., Colodro-Conde, L., Gordon, S. G., Madrid-Valero, J. J., Thalamuthu, A., Hottenga, J.-J., Mengel-From, J. & Armstrong, N. J. & 32 others, Sachdev, P., Lee, T., Brodaty, H., Trollor, J. N., Wright, M. J., Ames, D., Catts, V. S., Latvala, A., Vuoksimaa, E., Mallard, T. T., Harden, K. P., Tucker-drob, E. M., Oskarsson, S., Hammond, C. J., Christensen, K., Taylor, M. J., Lundström, S., Larsson, H., Karlsson, R., Pedersen, N. L., Mather, K. A., Medland, S. E., Boomsma, D. I., Martin, N. G., Plomin, R., Bartels, M., Lichtenstein, P., Kaprio, J., Eley, T., Davies, N. M., Munroe, P. B. & Keers, R., 10 Jun 2025, In: Nature Human Behaviour.Research output: Contribution to journal › Article › peer-review
Heritability of generalized anxiety stability: a longitudinal twin study among young adults
Funk (Student), J., Morneau-Vaillancourt, G., Palaiologou, E. & Eley, T., 30 Jun 2025, In: Psychological medicine. 55, e180.Research output: Contribution to journal › Article › peer-review
Investigating the genetic relationship between depression symptoms and Alzheimer’s Disease in clinically diagnosed and proxy cases
Gilchrist, L., Coleman, J., Howard, D., Adey, B., Davies, H. L., Mundy, J., ter Kuile, A., Davies, M., Bristow, S., Lee, S., Rogers, H., Curtis, C., Kalsi, G., Arathimos, R., Eley, T., Breen, G., Iacoangeli, A., Lewis, C. & Proitsi, P., 15 Jan 2025, In: Nature Mental Health .Research output: Contribution to journal › Article › peer-review
Peer problems and prosocial behaviours across development: associations with anxiety and depression in emerging adulthood
Morneau-Vaillancourt, G., Kwong, A. S. F., Thompson, K. V., Skelton, M., Thompson, E. J., Assary, E., Lockhart, C., Oginni, O. A., Palaiologou, E., McGregor, T., Arseneault, L. & Eley, T., 15 Jul 2025, In: Journal of affective disorders. 381, p. 360-371 12 p.Research output: Contribution to journal › Article › peer-review
Self-report measures of fear learning and extinction and their association with internet-based cognitive behavioural therapy outcome
McGregor, T., Carr, E., Davies, M., Kerr, T., Krebs, G., Purves, K., Skelton, M., Breen, G., Hirsch, C. & Eley, T., Apr 2025, In: Behaviour Research and Therapy. 187, 104705.Research output: Contribution to journal › Article › peer-review
Single-Item Patient-Rated Helpfulness and Improvement as an Alternative to Standardized Questionnaires for Establishing Anxiety and Depression Treatment Efficacy
Sewerynek, P., Wagner, C., McGregor, T., Skelton, M. & Eley, T., 10 Mar 2025, (Accepted/In press) In: Psychological Assessment.Research output: Contribution to journal › Article › peer-review
Software Application Profile: TIDAL – Tool to Implement Developmental Analysis of Longitudinal data
Kwong, A., Edmondson-Stait, A., Xu, E., Thompson, E. J., Parker, R. M. A., Elhakeem, A., Romaniuk, L., Pearson, R. M., Tilling, K., Eley, T., McIntosh, A. M. & Whalley, H., 6 Jul 2025, In: International Journal of Epidemiology.Research output: Contribution to journal › Article › peer-review
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell-types and pharmacotherapies
MDD Working Group of the Psychiatric Genomics Consortium, 6 Feb 2025, In: Cell. 188, 3, p. 640-652.e9Research output: Contribution to journal › Article › peer-review
UK Longitudinal Linkage Collaboration (UK LLC): The National Trusted Research Environment for Longitudinal Research
Boyd, A., Evans, K., Turner, E., Flaig, R., Oakley, J., Campbell, K., Thomas, R., McLachlan, S., Crane, M., Breen, G., Bristow, S., Das-Munshi, J., Eley, T., Fisher, H., Lockhart, C., Steves, C. & Chaturvedi, N., 17 Feb 2025, In: International Journal of Population Data Science. 10, 1, 06.Research output: Contribution to journal › Article › peer-review
Use of the FLARe Smartphone App in a Trauma-Exposed Sample: A Feasibility Study
Bountress, K. E., Latourrette, C., Purves, K. L., McGregor, T., Lasko, E., Dagher, A., Dick, D. M. & Eley, T., 1 Apr 2025, (Accepted/In press) In: Journal of Addictions Nursing.Research output: Contribution to journal › Article › peer-review
Causal and common risk pathways linking childhood maltreatment to later intimate partner violence victimization
Pezzoli, P., Pingault, J.-B., Eley, T. C., McCrory, E. & Viding, E., 1 Nov 2024, In: Molecular Psychiatry.Research output: Contribution to journal › Article › peer-review
Developmental Trajectories of Child and Adolescent Emotional Problems: associations with early adult alcohol use behaviors
Chen, T., Oginni, O. A., Hannigan, L. J., Eley, T. C., Maggs, J. L., Linden‐Carmichael, A. N. & Neiderhiser, J. M., 17 Dec 2024, In: Journal of child psychology and psychiatry. 66, 1, p. 85-97Research output: Contribution to journal › Article › peer-review
Genetics of environmental sensitivity and its association with variations in emotional problems, autistic traits, and wellbeing
Assary, E., Oginni, O. A., Morneau-Vaillancourt, G., Krebs, G., Palaiologou, E., Lockhart, C., Ronald, A. & Eley, T., 3 Mar 2024, In: Molecular Psychiatry. 29, 8, p. 2438-2446 9 p.Research output: Contribution to journal › Article › peer-review
Patterns of sub‐optimal change following CBT for childhood anxiety
Bertie, L., Arendt, K., Coleman, J. R. I., Cooper, P., Creswell, C., Eley, T. C., Hartman, C., Heiervang, E. R., In‐Albon, T., Krause, K., Lester, K. J., Marin, C. E., Nauta, M., Rapee, R. M., Schneider, S., Schniering, C., Silverman, W. K., Thastum, M., Thirlwall, K. & Waite, P. & 2 others, Wergeland, G. J. & Hudson, J. L., 30 May 2024, In: Journal of child psychology and psychiatry. 65, 12, p. 1612-1623Research output: Contribution to journal › Article › peer-review
Perinatal risk factors and subclinical hypomania: A prospective community study
Gonzalez-Calvo, I., Ronald, A., Shakoor, S., Taylor, M. J., Eley, T. & Hosang, G. M., 1 Oct 2024, In: Journal of affective disorders. p. 885-892Research output: Contribution to journal › Article › peer-review
Polygenic influences on networks of psychopathology symptoms: Unweaving the web
Piazza, G., Allegrini, A., Eley, T., Epskamp, S., Fried, E. I., Isvoranu, A.-M., Roiser, J. P. & Pingault, J.-B., 27 Mar 2024, (Accepted/In press) In: JAMA Psychiatry.Research output: Contribution to journal › Article › peer-review
Polygenic Scores and Networks of Psychopathology Symptoms
Piazza, G. G., Allegrini, A. G., Eley, T. C., Epskamp, S., Fried, E., Isvoranu, A.-M., Roiser, J. P. & Pingault, J.-B., 12 Jun 2024, (E-pub ahead of print) In: JAMA Psychiatry. 81, 9, p. 902-910Research output: Contribution to journal › Article › peer-review
Predicting remission following CBT for childhood anxiety disorders: a machine learning approach
Bertie, L.-A., Quiroz, J. C., Berkovsky, S., Arendt, K., Bögels, S., Coleman, J. R. I., Cooper, P., Creswell, C., Eley, T. C., Hartman, C., Fjermestadt, K., In-Albon, T., Lavallee, K., Lester, K. J., Lyneham, H. J., Marin, C. E., McKinnon, A., McLellan, L. F., Meiser-Stedman, R. & Nauta, M. & 10 others, Rapee, R. M., Schneider, S., Schniering, C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J., Wuthrich, V. & Hudson, J. L., 17 Dec 2024, (E-pub ahead of print) In: Psychological Medicine. p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
Using Bifactor Twin Modeling to Assess the Genetic and Environmental Dimensionality of Adult ADHD Symptoms
Knyspel, J., Morneau-Vaillancourt, G. & Eley, T. C., 30 Oct 2024, In: Behavior Genetics. 55, p. 1-11Research output: Contribution to journal › Article › peer-review
A cross-lagged twin study of emotional symptoms, social isolation, and peer victimisation from early adolescence to emerging adulthood
Morneau-Vaillancourt, G., Oginni, O., Assary, E., Krebs, G., Thompson, E., Palaiologou, E., Lockhart, C., Arseneault, L. & Eley, T., Nov 2023, In: Journal of Child Psychiatry & Psychology. 64, 11, p. 1569-1582 14 p.Research output: Contribution to journal › Article › peer-review
A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents
Peel, A., Oginni, O. A., Assary, E., Krebs, G., Lockhart, C., McGregor, T., Palaiologou, E., Ronald, A., Danese, A. & Grant, T. E., 13 Feb 2023, In: Journal of Child Psychology and Psychiatry.Research output: Contribution to journal › Article › peer-review
A multivariate twin study of the genetic association between present moment attention and subjective wellbeing
Brown, K. W., Aliev, F., Eley, T., Dick, D. M. & Sawyers, C., 14 Oct 2023, In: Scientific Reports.Research output: Contribution to journal › Article › peer-review
Bidirectional causal associations between same-sex attraction and psychological distress: Testing moderation and mediation effects
Oginni, O. A., Lim, K., Rahman, Q., Jern, P., Grant, T. E. & Rijsdijk, F., Mar 2023, In: Behavior Genetics. 53, 2, p. 118–131 14 p.Research output: Contribution to journal › Article › peer-review
Differential susceptibility theory: might it help in understanding and treating mental health problems in youth?
Assary, E., Krebs, G. & Eley, T., 7 Jul 2023, In: Journal of Child Psychology and Psychiatry. 64, 8, p. 1104-1114 11 p.Research output: Contribution to journal › Review article › peer-review
Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies
Waszczuk, M. A., Jonas, K. G., Bornovalova, M., Breen, G., Bulik, C. M., Docherty, A. R., Eley, T. C., Hettema, J. M., Kotov, R., Krueger, R. F., Lencz, T., Li, J. J., Vassos, E. & Waldman, I. D., 4 Jul 2023, (E-pub ahead of print) In: Molecular Psychiatry. 11 p.Research output: Contribution to journal › Article › peer-review
Evidence for distinct genetic and environmental influences on fear acquisition and extinction
Purves, K. L., Krebs, G., McGregor, T., Constantinou, E., Lester, K., Barry, T., Craske, M. G., Young, K., Breen, G. & Eley, T. C., Feb 2023, In: Psychological Medicine.Research output: Contribution to journal › Article › peer-review
Factors associated with anxiety disorder comorbidity
Davies, M. R., Glen, K., Mundy, J., Adey, B., Armour, C., Assary, E., Coleman, J., Goldsmith, K., Hirsch, C., Hotopf, M., Hübel, C., Jones, I., Kalsi, G., Krebs, G., McIntosh, A. M., Morneau-Vaillancourt, G., Peel, A., Purves, K., Lee, S. & Skelton, M. & 7 others, Smith, D. J., Veale, D., Walters, J., Young, K., Zvrskovec, J., Breen, G. & Grant, T. E., 15 Feb 2023, In: Journal of Affective Disorders. 323, p. 280-291 12 p.Research output: Contribution to journal › Article › peer-review
Genetic decomposition of the heritable component of reported childhood maltreatment
ter Kuile, A., Hübel, C., Cheesman, R., Coleman, J., Peel, A., Levey, D. F., Stein, M. B., Gelernter, J., Rayner, C., Eley, T. & Breen, G., 6 Jun 2023, In: Biological Psychiatry: Global Open Science. 3, 4, p. 716-724 9 p.Research output: Contribution to journal › Article › peer-review
Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder
Mundy, J., Hübel, C., Adey, B., Davies, H., Davies, M. R., Coleman, J., Hotopf, M., Kalsi, G., Lee, S. H., M. McIntosh, A., Rogers, H., Eley, T., Murray, R., Vassos, E. & Breen, G., 1 Oct 2023, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 192, 7-8, p. 147-160 14 p.Research output: Contribution to journal › Article › peer-review
Introducing the Fear Learning and Anxiety Response (FLARe) app and web portal for the remote delivery of fear conditioning experiments
McGregor, T., Purves, K., Barry, T., Constantinou, E., Craske, M. G., Breen, G., Young, K. & Eley, T., Sept 2023, In: Behaviour Research Methods.Research output: Contribution to journal › Article › peer-review
Networks of Neurodevelopmental Traits, Socioenvironmental Factors, Emotional Dysregulation in Childhood, and Depressive Symptoms Across Development in Two U.K. Cohorts
Farhat, L. C., Blakey, R., Davey Smith, G., Fujita, A., Shephard, E., Stergiakouli, E., Eley, T. C., Thapar, A. & Polanczyk, G. V., 1 Oct 2023, In: American Journal of Psychiatry. 180, 10, p. 755-765Research output: Contribution to journal › Article › peer-review
Predicting prognosis for adults with depression using individual symptom data: a comparison of modelling approaches
Buckman, J. E. J., Cohen, Z. D., O'Driscoll, C., Fried, E. I., Saunders, R., Ambler, G., DeRubeis, R. J., Gilbody, S., Hollon, S. D., Kendrick, T., Watkins, E., Eley, T. C., Peel, A. J., Rayner, C., Kessler, D., Wiles, N., Lewis, G. & Pilling, S., Jan 2023, In: Psychological Medicine. p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
Research priorities in psychiatric genetic counselling: how to talk to children and adolescents about genetics and psychiatric disorders
Mundy, J., Davies, H. L., Radu, M., Austin, J., Vassos, E., Eley, T. C., Breen, G. & Moldovan, R., Mar 2023, In: European Journal of Human Genetics. 31, 3, p. 262-264 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Seeking help for mental health during the COVID-19 pandemic: A longitudinal analysis of adults’ experiences with digital technologies and services
Parsons, C. E., Purves, K. L., Davies, M. R., Mundy, J., Bristow, S., Eley, T. C., Breen, G., Hirsch, C. R. & Young, K. S., 1 Dec 2023, In: PLOS digital health. 2, 12, e0000402.Research output: Contribution to journal › Article › peer-review
Sociodemographic, mental health, and physical health factors associated with participation within re-contactable mental health cohorts: an investigation of the GLAD Study
Bright, S. J., Hübel, C., Young, K. S., Bristow, S., Peel, A. J., Rayner, C., Mundy, J., Palmos, A. B., Purves, K. L., Kalsi, G., Armour, C., Jones, I. R., Hotopf, M., McIntosh, A. M., Smith, D. J., Walters, J. T. R., Rogers, H. C., Thompson, K. N., Adey, B. N. & Monssen, D. & 9 others, Kakar, S., Malouf, C. M., Hirsch, C., Glen, K., Kelly, E. J., Veale, D., Eley, T. C., Breen, G. & Davies, M. R., Dec 2023, In: BMC Psychiatry. 23, 1, 542.Research output: Contribution to journal › Article › peer-review
The conditional associations between neurodevelopmental traits, social-environmental stressors, and emotional dysregulation in childhood and depressive symptoms over development: a Bayesian multivariate analysis of two UK cohorts
Farhat, L. C., Farhat, L. C., Smith, G. D., Fujita, A., Shephard, E., Stergiakouli, E., Eley, T., Thapar, A. & Polanczyk, G., 24 May 2023, (Accepted/In press) In: Journal of Psychiatry.Research output: Contribution to journal › Article › peer-review
The network structure of mania symptoms differs between people with and without binge eating
Davies, H. L., Peel, A. J., Mundy, J., Monssen, D., Kakar, S., Davies, M. R., Adey, B. N., Armour, C., Kalsi, G., Lin, Y., Marsh, I., Rogers, H. C., Walters, J. T. R., Herle, M., Glen, K., Malouf, C. M., Kelly, E. J., Eley, T. C., Treasure, J. & Breen, G. & 1 others, Hübel, C., Nov 2023, In: Bipolar Disorders. 25, 7, p. 592-607 16 p.Research output: Contribution to journal › Article › peer-review
The p factor of psychopathology and personality in middle childhood: Genetic and gestational risk factors
Gjerde, L. C., Eilertsen, E. M., McAdams, T. A., Cheesman, R., Moffitt, T. E., Caspi, A., Eley, T. C., Roysamb, E., Rosenström, T. H. & Ystrom, E., 10 Jul 2023, In: Psychological Medicine. 53, 9, p. 4275-4285 11 p.Research output: Contribution to journal › Article › peer-review
The p factor of psychopathology and personality in middle childhood: Genetic and gestational risk factors - Corrigendum
Gjerde, L. C., Eilertsen, E. M., McAdams, T. A., Cheesman, R., Moffitt, T. E., Caspi, A., Eley, T. C., Røysamb, E., Rosenström, T. H. & Ystrom, E., 1 Jul 2023, In: Psychological Medicine. 53, 9, p. 4303-4304 2 p.Research output: Contribution to journal › Article › peer-review
The relationship between weight-related indicators and depressive symptoms during adolescence and adulthood: results from two twin studies
Thompson, E. J., Krebs, G., Zavos, H., Steves, C. & Eley, T., 31 Aug 2023, (E-pub ahead of print) In: Psychological medicine.Research output: Contribution to journal › Article › peer-review
The relationship between weight-related indicators and depressive symptoms during adolescence and adulthood: results from two twin studies
Thompson, E. J., Krebs, G., Zavos, H., Steves, C. & Eley, T., 31 Aug 2023, In: Psychological medicine.Research output: Contribution to journal › Article › peer-review
The United Kingdom Eating Disorders Genetics Initiative
Monssen, D., Davies, H., Kakar, S., Curzons, S., Davies, M., Kelly, E., Ahmad, Z., Bradley, J. R., Bright, S. J., Coleman, J., Glen, K., Hotopf, M., ter Kuile, A., Malouf, M., Kalsi, G., Kingston, N., McAtarsney-Kovacs, M., Mundy, J., Peel, A. & Palmos, A. & 12 others, Rogers, H., Skelton, M., Adey, B., Lee, S.-H., Virgo, H., Quinn, T., Price, T., Zvrskovec, J., Eley, T., Treasure, J., Hübel, C. & Breen, G., 16 Aug 2023, In: International Journal of Eating Disorders. p. 1-15 15 p.Research output: Contribution to journal › Article › peer-review
Trajectories of depression and anxiety symptom severity during psychological therapy for common mental health problems
Skelton, M., Carr, E., Buckman, J. E. J., Davies, M. R., Goldsmith, K., Hirsch, C. R., Peel, A. J., Rayner, C., Rimes, K., Saunders, R., Wingrove, J., Breen, G. & Grant, T. E., 25 Sept 2023, In: Psychological Medicine. 53, 13, p. 6183-6193 11 p.Research output: Contribution to journal › Article › peer-review
Trajectories of depression symptoms, anxiety symptoms and functional impairment during internet-enabled cognitive-behavioural therapy
Skelton, M., Catarino, A., Brown, S., Carr, E., Davies, M., Peel, A. J., Rayner, C., Breen, G. & Eley, T., 12 Aug 2023, (Accepted/In press) In: Behaviour Research and Therapy.Research output: Contribution to journal › Article › peer-review
Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties.
Lockhart, C., Bright, J., Ahmadzadeh, Y., Breen, G., Bristow, S., Boyd, A., Downs, J., Hotopf, M., Palaiologou, E., Rimfeld, K., Maxwell, J., Malachini, M., McAdams, T. A., McMillan, A., Plomin, R. & Eley, T. C., 30 Mar 2023, In: JCPP Advances.Research output: Contribution to journal › Article › peer-review
Comparison of symptom-based versus self-reported diagnostic measures of anxiety and depression disorders in the GLAD and COPING cohorts
Davies, M. R., Buckman, J. E. J., Adey, B. N., Armour, C., Bradley, J. R., Curzons, S. C. B., Davies, H. L., Davis, K. A. S., Goldsmith, K. A., Hirsch, C. R., Hotopf, M., Hübel, C., Jones, I. R., Kalsi, G., Krebs, G., Lin, Y., Marsh, I., McAtarsney-Kovacs, M., McIntosh, A. M. & Mundy, J. & 12 others, Monssen, D., Peel, A. J., Rogers, H. C., Skelton, M., Smith, D. J., Ter Kuile, A., Thompson, K. N., Veale, D., Walters, J. T. R., Zahn, R., Breen, G. & Eley, T. C., Jan 2022, In: Journal of Anxiety Disorders. 85, 102491.Research output: Contribution to journal › Article › peer-review
Research

TEDS: Twins Early Development Study
The Twin Early Development Study (TEDS) is one of the leading large-scale twin studies in the world. Starting in 1994, it has followed twins born in England and Wales throughout their childhood and adolescence and has now continued into early adulthood.

The Emotional Development, Interventions and Treatment (EDIT) Lab
The EDIT lab is led by Prof Thalia Eley and consists of post doctoral researchers, PhD students, and both undergraduate and masters students. We study genetic and environmental influences on the development and treatment of anxiety and depression. We are based at the SGDP Centre at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London.

GLAD: Genetic Links to Anxiety and Depression
The GLAD Study is the largest anxiety and depression project ever undertaken. It was launched in September 2018.
Project status: Ongoing

Children of TEDS (CoTEDS) Study
The aim of this project is to explore the origins of the development of emotional disorders.
Project status: Ongoing

FLARe: Fear Learning and Anxiety Response
FLARe aims to model the processes underlying the development, maintenance and treatment of anxiety disorders, and post-treatment relapse.
Project status: Ongoing

G1219: Genesis 1219
G1219 is a longitudinal study that aims to examine the interplay between genes and the environment on the development of anxiety and depression over time.
Project status: Completed

Repeated Assessment of Mental health in Pandemics (RAMP)
The Repeated Assessment of Mental health in Pandemics (RAMP) study is a research project assessing the effect of COVID-19 on the mental health and wellbeing of the population.

Learning Effective New Strategies (LENS)
LENS (Learning Effective New Strategies) is a digital therapy shown to reduce anxiety and depression.
Project status: Ongoing
News
Professor Thalia Eley elected a Fellow of the British Academy
Professor Eley joins 92 new Fellows welcomed to the prestigious British Academy, in recognition of scholarly distinction in the humanities and social sciences.

Largest twin study explores whether the environment affects people differently depending on their genes
Researchers at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London, University College London, Queen Mary University of...

£4.8 million Wellcome funding to predict outcomes following anxiety treatment
Wellcome has awarded over £4.8m for researchers to predict individual outcomes following psychological treatments for anxiety, and to identify genetic and...

UK Longitudinal Linkage Collaboration awarded £6.4m
New funding from MRC/ESRC will allow partnership between leading UK longitudinal studies, including King’s-led studies GLAD and EDGI UK will enable...

Professor Thalia Eley elected as Fellow of the Academy of Medical Sciences
Professor Eley is one of 50 new Fellows to be elected to the prestigious Academy of Medical Sciences

Twins Early Development Study receives £3.2million funding from MRC
Successful grant renewal from Medical Research Council (MRC) will fund pioneering Twin Early Development Study until 2025.

Features
Exploring research into anxiety disorders this Mental Health Awareness Week
This year, Mental Health Awareness Week took place Monday 15 - Sunday 21 June, following the theme ‘anxiety’. Anxiety is a normal emotion in us all, but...
